DNA Typing Profiles

Trade Agreement: CETA / CFTA Tendering Procedures: All interested suppliers may submit a bid Competitive Procurement Strategy: Best Overall Proposal Comprehensive Land Claim Agreement: No Nature of Requirements:

M7594-173247/A

PROFESSIONAL SERVICES CONSISTING OF DNA TYPING SERVICES The objective is to provide the National DNA Data Bank (NDDB) of the Royal Canadian Mounted Police (RCMP) with DNA typing services to support the investigation of missing persons and unidentified human remains in support of the National Missing Persons DNA Program (NMPDP). The period of any resulting contract will be from date of Contract award to March 31st, 2019 inclusive. Any resulting contract will include an irrevocable option to extend the resulting contract term by up to four (4) additional one (1) year periods under the same conditions.

Up to two contracts can be awarded for this requirement (one for each stream).

The NDDB requires the following services on an as and when requested basis: a) Stream 1 - Autosomal and Y-STR DNA Profile Development Service & Hard Tissue Preparation Service

1. Development of Autosomal and Y-STR DNA profiles A Contractor must process biological samples, including missing person samples, family reference samples and human remain samples (soft and hard tissue), and characterize these samples as follows: i. Autosomal STR analysis that tests, at a minimum, the original thirteen (13) core CODIS loci. DNA information at additional CODIS loci will also be accepted for review by the NDDB (See Appendix 1). ii. Y-STR analysis that tests the CODIS Y-STR loci (See Appendix 2).

2. Preparation of Hard Tissue Samples for Subsequent DNA Analysis by the NDDB A Contractor is required to prepare hard tissue samples from human remains, such as bone and teeth, for subsequent DNA profile development by the NDDB. The Contractor must be capable of pulverizing hard tissue samples into a powder suitable for DNA extraction: i. The process must not introduce any foreign/contaminating DNA during the sample preparation process. ii. The DNA profiles from personnel responsible for the sample preparation must be provided by the Contracting Laboratory. The identifiers for these DNA profiles are to be coded by the Contractor so as not to reveal the name of the individual. These DNA profiles are required for contamination monitoring by the NDDB.

b) Stream 2 Mitochondrial DNA Sequencing Service for Missing Person Samples, Family Reference Samples and Human Remain Samples 1. Mitochondrial DNA Sequencing Service A Contractor is required to process missing person samples, family reference samples and human remain samples (soft and hard tissue), and characterize those samples at the following genetic regions: i. Hypervariable Region 1 (HV1: minimum range from position 16024 to 16365) and Hypervariable Region 2 (HV2: minimum range from position 73 to 340) of mitochondrial DNA. (Appendix 3)

The requirement is not subject to the provisions of the North American Free Trade Agreement (NAFTA); and the World Trade Organization Agreement (WTO-AGP). The requirement is subject to the provisions of the Canadian Free Trade Agreement (CFTA).

The Federal Contractors Program (FCP) for employment equity applies to this procurement. Contracting Authority: St-Cyr, Audrey Acquisitions Branch 10, rue Wellington, Gatineau (QC), K1A 0S5 613-858-9049 Audrey.st-cyr@tpsgc-pwgsc.gc.ca Delivery Date: Above-mentioned

The Crown retains the right to negotiate with suppliers on any procurement.

Documents may be submitted in either official language of Canada.