Automatic protein digestion instrument

Trade Agreement: NAFTA / CFTA / FTAs with Peru / Colombia / Panama / Korea Tendering Procedures: Generally only one firm has been invited to bid Non-Competitive Procurement Strategy: Exclusive Rights Comprehensive Land Claim Agreement: No Vendor Name and Address: Intavis Bioanalytical Instruments 3106 N. Ashland Avenue, #249 CHICAGO Illinois United States 60657 Nature of Requirements:

Automatic protein digestion instrument

H4075-184113/A O’Gorman, Cindy

1. Advance Contract Award Notice (ACAN)

An ACAN is a public notice indicating to the supplier community that a department or agency intends to award a contract for goods, services or construction to a pre-identified supplier, thereby allowing other suppliers to signal their interest in bidding, by submitting a statement of capabilities. If no supplier submits a statement of capabilities that meets the requirements set out in the ACAN, on or before the closing date stated in the ACAN, the contracting officer may then proceed with the award to the pre-identified supplier.

2. Definition of the requirement

Health Canada’s (HC) Health Products and Food Branch (HPFB) Food Research Division requires the supply and delivery of an automatic protein digestion instrument to automate the digestion, desalting and clean-up of food protein samples prior to analysis by mass spectrometry.

The system must allow for protein digestion to be done unattended, thereby reducing the backlog and minimizing the variability with current manual sample preparation methods. A DigestPro MSi system from Intavis that includes the following upgrade modules is identified to meet all mandatory requirements.

-In-Gel Digestion with cooled collection position 96 well format instead of ambient collection position

-In-solution digestion - Custom Rack - Can be cooled and heated, temperature range (8°C - 70°C).

-sample desalting and concentration/purification - 96 well format with Zip Tips (TM for Millipore Corp.) or compatible reversed phase tips

3. Criteria for assessment of the Statement of Capabilities (Minimum Essential Requirements)

-The instrument must digest up to 96 samples per run in a sealed system to prevent contamination of samples.

-The system must perform all of the required steps for both in-gel and in-solution digestions including, but not limited to the following: *reduction; *alkylation; *digestion; *silver reduction; *washing steps

-The system must also deliver, enable and support the ability to heat (up to 80°C) or cool samples (down to 8°C)

-The system must deliver, enable and support the ability to integrate solid-phase clean-up of samples (Example C-18) and sample enrichment.

-The sample and reagent vial holder must deliver, enable and support the ability to be temperature regulated between 8-65°C.

-The system must be expandable to accept a wide variety of sample and reagent vials or plates.

4. Applicability of the trade agreements to the procurement

This procurement is subject to the following trade agreements -Canada Free Trade Agreement (CFTA) -North American Free Trade Agreement (NAFTA)

5. Justification for the Pre-Identified Supplier

Intavis Inc. is the only supplier that can supply a system meeting all the technical requirements and has the exclusive rights for the DigestPro Msi system.

6. Government Contracts Regulations Exceptions

The following exception to the Government Contracts Regulations is invoked for this procurement under subsection 6(d) - "only one person is capable of performing the work".

7. Exclusions and/or Limited Tendering Reasons

The following exclusions and/or limited tendering reasons are invoked under the -Canada Free Trade Agreement (CFTA) - Article 513.1(b)(iii) -North American Free Trade Agreement (NAFTA) - Article 1016.2(b)

8. Period of the proposed contract or delivery date

The system must be delivered on or before March 29th, 2019.

9. Name and address of the pre-identified supplier

Intavis, Inc. 945 W George, Suite 201 Chicago, IL 60657-5893

10. Suppliers' right to submit a statement of capabilities

Suppliers who consider themselves fully qualified and available to provide the goods described in the ACAN may submit a statement of capabilities in writing to the contact person identified in this notice on or before the closing date of this notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements.

11. Closing date for a submission of a statement of capabilities

The closing date and time for accepting statements of capabilities is February 5, 2019 at 2:00 p.m. EST.

12. Inquiries and submission of statements of capabilities

Cindy O’Gorman Supply Specialist Scientific, Medical and Photographic Division - PV Public Services and Procurement Canada, Acquisitions Program Government of Canada L’Esplanade Laurier, East Tower, 7th floor 140 O'Connor St., Ottawa, Ontario K1A 0S5

E-mail: Cindy.O’Gorman@tpsgc-pwgsc.gc.ca

Delivery Date: Above-mentioned

You are hereby notified that the government intends to negotiate with one firm only as identified above. Should you have any questions concerning this requirement, contact the contracting officer identified above.

An Advance Contract Award Notice (ACAN) allows departments and agencies to post a notice, for no less than fifteen (15) calendar days, indicating to the supplier community that it intends to award a good, service or construction contract to a pre-identified contractor. If no other supplier submits, on or before the closing date, a Statement of Capabilities that meets the requirements set out in the ACAN, the contracting authority may then proceed with the award. However, should a Statement of Capabilities be found to meet the requirements set out in the ACAN, then the contracting authority will proceed to a full tendering process.

Suppliers who consider themselves fully qualified and available to provide the services/goods described herein, may submit a statement of capabilities in writing to the contact person identified in this Notice on or before the closing date of this Notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements.

The PWGSC file number, the contracting officer's name and the closing date of the ACAN must appear on the outside of the envelope in block letters or, in the case of a facsimile transmission, on the covering page.

The Crown retains the right to negotiate with suppliers on any procurement.

Documents may be submitted in either official language of Canada.