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Create free accountTrade Agreement: NAFTA/AIT/Canada FTAs with Peru/Colombia/Panama Tendering Procedures: All interested suppliers may submit a bid Attachment: None Non-Competitive Procurement Strategy: Interchangeable Parts Comprehensive Land Claim Agreement: No Vendor Name and Address: NanoSight 6660 N High Street, Suite 2A Worthington Ohio United States 43085 Nature of Requirements: Particle Characterization System
6D063-132291/A Wiebe, Amanda Telephone No. - (204) 983-7032 Fax No. - (204) 983-7796
ADVANCED CONTRACT AWARD NOTICE An ACAN is a public notice indicating to the supplier community that a department or agency intends to award a contract for goods, services or construction to a pre-identified supplier, thereby allowing other suppliers to signal their interest in bidding, by submitting a statement of capabilities. If no supplier submits a statement of capabilities that meets the requirements set out in the ACAN, on or before the closing date stated in the ACAN, the contracting officer may then proceed with the award to the pre-identified supplier.
DEFINITION OF THE REQUIREMENT
The Public Health Agency of Canada - National Microbiology Laboratory has a requirement for the supply and delivery/installation of a Particle Characterization System.
The National Microbiology Laboratory (NML) Electron Microscope laboratory provides a service for all NML scientists. NML endeavors to provide images of the various pathogens being investigated. At present the facility has two electron microscopes, a transmission electron microscope, and scanning electron microscope. These microscopes are used to image viruses, bacteria, and tissue culture cells which have been infected with a pathogen. The particle characterization system required will be used to access the heterogeneity of biological samples being imaged, and calculate particle concentration. As well, the system will be used to access biological reactions such as virus - liposome fusion and the ability of various reagents to impede this key process in viral attachment and penetration into the host cell. This will provide fundamental information for the development of vaccines and antivirals. The system must meet all of the essential requirements listed below.
MINIMUM ESSENTIAL REQUIREMENTS
Any interested supplier must demonstrate by way of a statement of capabilities that its product meets the following requirements: Item Description 1 The system will be used for heterogeneous biological samples, the system must be able to differentiate and identify particles in a liquid suspension that contains particles of different sizes. Particle detection range must at least encompass the size range of 30 nm -1um. 2 Unknown biological samples/fluids will be processed; the chemical or biological composition of the fluids will be unknown. The system must not need to know anything about the liquid being analyzed (eg. refractive index or particle density information) in order to determine the size distribution of the samples being analyzed. 3 The system must be able measure particle concentration. 4 The system must operate on standard North American voltage (110 V AC). 5 The system must include one PC, with pre-loaded software to operate the particle counter, and also include a flat screen monitor, that is 22" or larger 6 The system must use a CMOS (Complementary Metal-Oxide-Semiconductor) high sensitivity camera to detect particles. (i.e. not a CCD [charge coupled device] camera) 7 The system must have fluorescent filters to detect and image fluorescent labeled samples. 8 The system must have temperature control with a sensitivity of 0.5oC or better 9 The system must use peristaltic pumps controlled by the system software. 10 The system must have at least one syringe pump controlled by the system software. 11 The system must include a color laser printer. 12 The system must be able to measure particles at concentrations as low as 107 particles / ml or lower. 13 Minimum OEM Warranty - 1 year
JUSTIFICATION FOR THE PRE-IDENTIFIED SUPPLIER
The Nanosight system is a unique piece of equipment, in both its methodology (ability to detect particles in heterogeneous samples) and their level of automation. Various equipment from alternate suppliers was evaluated and none could match all the minimal essential requirements detailed above.
Diagnostics: The "diagnostic capacity" will be used to identify unknown samples that arrive at the laboratory. To date electron microscopy has been used for identification in the diagnostic microscopy laboratory. The equipment being requested will provide a rapid complementary method to screen samples. In this instance the equipment will analyze the sample for size distribution to identify the presence of particles of a specific size range. This data will assist the electron microscopy analysis by indicating the presence of a particle (putative virus) of a specific size range in the diagnostic sample being processed.
Research & Development: Several activities fall under this type of work done in the lab ranging from; virus like particle production, development of antivirals, working with fluorescently labeled viruses and vesicles, and the investigation of virus-host interactions using a vesicle based system which includes virus host cell fusion and the effect of temperature, pH, and enzymatic cleavage/processing of the viral spike necessary for spike-receptor binding. In all the above cases the "Particle Characterization System" being requested will be essential in the research and development process to study these dynamic systems. This "Particle Characterization System" will provide "real time" bio-physical kinetic data on these projects that we currently are not able to do. With this equipment NML will be able to study in "real time" virus host fusion, characterize this, and then measure the effects of antiviral agents on this process.
APPLICABILITY OF THE TRADE AGREEMENTS TO THIS PROCUREMENT This procurement is subject to the following trade agreements:
Agreement on Internal Trade (AIT) North American Free Trade Agreement (NAFTA) Canada - Chile Free Trade Agreement (CCFTA) Canada - Peru Free Trade Agreement (CPFTA) Canada - Columbia Free Trade Agreement (CCFTA)
GOVERNMENT CONTRACTS REGULATIONS EXCEPTIONS
The following exception(s) to the Government Contracts Regulations is (are) invoked for this procurement under subsection: Government Contract Regulations, Part 1, Section 6(d) only one supplier (person or firm) is capable of performing the contract.
EXCLUSIONS AND/OR LIMITED TENDERING REASONS The following exclusions and/or limited tendering reasons are invoked under the:
Agreement on Internal Trade (AIT) - Article 506 - 12 (b) where there is an absence of competition for technical reasons and the goods or services can be supplied only by a particular supplier and no alternative or substitute exist.
North American Free Trade Agreement (NAFTA) - Article 1016 - 2 (b) where, for works of art, or for reasons connected with the protection of patents, copyrights or other exclusive rights, or proprietary information or where there is an absence of competition for technical reasons, the goods or services can be supplied only by a particular supplier and no reasonable alternative or substitute exists.
Canada - Chile Free Trade Agreement (CCFTA) - Article Kbis-09 - 1(b) where, for works of art, or for reasons connected with protection of patents, copyrights or other exclusive rights, or proprietary information, or where there is an absence of competition for technical reasons, the goods or services can be supplied only by a particular supplier and no reasonable alternative or substitute exists.
Canada - Peru Free Trade Agreement (CPFTA) - Article 1409 1(b) where the goods or services can be supplied only by a particular supplier and no reasonable alternative or substitute goods or services exist for any of the following reasons: (i) the requirement is for a work of art, (ii) the protection of patents, copyrights or other exclusive rights, or (iii) due to an absence of competition for technical reasons;
Canada - Columbia Free Trade Agreement (CCFTA) - Article 1409 1(b)Where the goods or services can be supplied only by a particular supplier and no reasonable alternative or substitute goods or services exist for any of the following reasons:
i.The requirement is for a work of art, ii.The protection of patents, copyrights or other exclusive rights, or iii.Due to an absence of competition for technical reasons;
DELIVERY DATE The equipment must be delivered on or before March 31, 2014 .
NAME AND ADDRESS OF THE PRE-IDENTIFIED SUPPLIER
Nanosight USA 6660 N High Street, Suite 2A Worthington, OH 43085
SUPPLIERS' RIGHT TO SUBMIT A STATEMENT OF CAPABILITES
Suppliers who consider themselves fully qualified and available to provide the goods, services or construction services described in the ACAN may submit a statement of capabilities in writing to the contact person identified in this notice on or before the closing date of this notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements.
CLOSING DATE FOR A SUBMISSION OF A STATEMENT OF CAPABILITIES
The closing date and time for accepting statements of capabilities is:Friday. Dec. 6, 2013 .
INQUIRIES AND SUBMISSION OF STATEMENTS OF CAPABILITIES
Amanda Wiebe Supply Officer | Agente d'approvisionnement Public Works and Government Services Canada Travaux publics et Services gouvernement aux Canada Acquisitions Branch | Direction générale des approvisioinnements 100 - 167 Lombard Avenue, Winnipeg, MB, R3C 2Z1 |167, av. Lombard, pièce 100, Winnipeg, (MB), R3C 2Z1
Tel | Tél: (204) 983-7032 Fax | Téléc: (204) 983-7796 Email | Courriel: amanda.wiebe@pwgsc-tpsgc.gc.ca Delivery Date: Above-mentioned
You are hereby notified that the government intends to negotiate with one firm only as identified above. Should you have any questions concerning this requirement, contact the contracting officer identified above.
An Advance Contract Award Notice (ACAN) allows departments and agencies to post a notice, for no less than fifteen (15) calendar days, indicating to the supplier community that it intends to award a good, service or construction contract to a pre-identified contractor. If no other supplier submits, on or before the closing date, a Statement of Capabilities that meets the requirements set out in the ACAN, the contracting authority may then proceed with the award. However, should a Statement of Capabilities be found to meet the requirements set out in the ACAN, then the contracting authority will proceed to a full tendering process.
Suppliers who consider themselves fully qualified and available to provide the services/goods described herein, may submit a statement of capabilities in writing to the contact person identified in this Notice on or before the closing date of this Notice. The statement of capabilities must clearly demonstrate how the supplier meets the advertised requirements.
The PWGSC file number, the contracting officer's name and the closing date of the ACAN must appear on the outside of the envelope in block letters or, in the case of a facsimile transmission, on the covering page.
The Crown retains the right to negotiate with suppliers on any procurement.
Documents may be submitted in either official language of Canada.
Not stated in the notice: procurement type, procurement method, selection criteria, region of delivery, region of opportunity, expected contract period, end user
No amendments observed.
No attachments listed in the open data.
No contact listed in the open data.