Capillary electrophoresis system

Trade Agreement: WTO-AGP/NAFTA/AIT/Canada FTAs with Peru/Colombia/Panama Tendering Procedures: Attachment: None Competitive Procurement Strategy: Lowest/Lower Bid Comprehensive Land Claim Agreement: No Nature of Requirements: The National Research Council of Canada (NRC) - Montreal Royalmount wants to expand its capabilities in biophysical characterization of macromolecules and macromolecular assemblies in support of industrial clients and internal projects in the Biologics and Vaccines programs. Analysis of antibodies and derivatives (Fab, Fc, Fc fusions) will consitute a significant fraction of the analyses anticipated, but other candidate biotherapeutics or vaccines which are anticipated to be analyzed include other proteins, nucleic acids, polysaccharides, polymers, nanoparticles and virus-like particles. Among the essential characterizations for any candidate biotherapeutic or vaccine is the purity, molecular size, and homogeneity with respect to charge and glycosylation variants. Capillary electrophoresis is an increasingly recognized approach accepted by regulatory agencies as a methodology for characterization of molecular size, charge, purity and homogeneity.

Since this capability is currently lacking at the NRC-Montreal Royalmount, the NRC wishes to purchase a capillary electrophoresis system.

The work consists of supply, delivery, installation of the system at the NRC address and training on equipment use; all of the work must be completed preferably by January 31st, 2014 but mandatory before March 31, 2014.

Delivery Date: Above-mentioned

The Crown retains the right to negotiate with suppliers on any procurement.

Documents may be submitted in either official language of Canada.