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High throughput device for rapid cellular metabolic characterization | National Research Council of Canada (NRC) · CanPursue
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High throughput device for rapid cellular metabolic characterization

National Research Council of Canada (NRC)25-58185Federal
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Published
Oct 29, 2025
Respond by
Nov 25, 2025
Latest amendment
—2 amendments

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Description

Description

OBJECTIVE: The cell culture scale-up team (CCSU) has a requirement for an instrument for rapid cellular metabolic characterization. The instrument will be used to characterize and screen the phenotype and the metabolic requirements of cell lines developed at the NRC and used in large-scale bioreactors.

BACKGROUND: Cell lines can be used to produce monoclonal antibodies, recombinant proteins, viral vectors, vaccines, viruses and virus-like-particles. In large-scale bioreactor, the metabolic profile of a cell line has a critical impact on its productivity. The presence of certain nutrients in the cell culture media is also a strong determinant of the cell line performance. Therefore, we are looking for an instrument that will enable measurements of multiple metabolites in parallel at 32oC to 37oC in live cells. We are particularly interested in measurements of metabolites involved in mitochondrial activity and respiration. We also need to screen different compounds that might improve cell growth and productivity in a high-throughput fashion.

All the deliverables must be received within 2 months after the contract award date.

Procurement

Category
Goods
Jurisdiction
Federal

Not stated in the notice: procurement type, procurement method, selection criteria, region of delivery, region of opportunity, expected contract period, end user

Requirements and qualifications

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Not stated in the public notice
Security requirement
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Trade agreements
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Limited tendering reason
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Classification

GSIN
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UNSPSC
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Amendments

The source reports 2 amendments. CanPursue observed 1 of them with dates.

  • Amendment 2Nov 25, 2025
  • Original noticeOct 29, 2025

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Source

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Source
CanadaBuys
Solicitation
25-58185
Observed
Sep 27, 2026

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